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Azilsartan

Chemical Structure : Azilsartan

CAS No.: 147403-03-0

Azilsartan (TAK-536, TAK536)

货号: PC-44124Not For Human Use, Lab Use Only.

Azilsartan (TAK-536) is a specific and potent angiotensin II type 1 receptor (AT1) antagonist with IC50 of 2.6 nM, used in the treatment of adults with essential hypertension.

规格 价格 库存 数量
25 mg ¥1280 In stock
50 mg ¥1980 In stock
100 mg ¥2980 In stock
200 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Azilsartan (TAK-536) is a specific and potent angiotensin II type 1 receptor (AT1) antagonist with IC50 of 2.6 nM, used in the treatment of adults with essential hypertension.

物理化学性质&存储条件

分子量 456.4501
分子式 C25H20N4O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1H-Benzimidazole-7-carboxylic acid, 1-[[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-

参考文献

1. French C, et al. J Cardiovasc Pharmacol. 2011 Aug;58(2):143-8.

2. Kusumoto K, et al. Eur J Pharmacol. 2011 Nov 1;669(1-3):84-93.

3. Bönner G, et al. J Hum Hypertens. 2013 Aug;27(8):479-86.

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