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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Wee1-Azenosertib
Azenosertib

Chemical Structure : Azenosertib

CAS No.: 2376146-48-2

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Azenosertib (ZN-c3, Wee1 inhibitor ZN-c3)

货号: PC-72320Not For Human Use, Lab Use Only.

Azenosertib (ZN-c3, Wee1 inhibitor ZN-c33) is a highly potent, selective Wee1 inhibitor with IC50 of 3.8 nM.

规格 价格 库存 数量
5 mg ￥1580 In stock
10 mg ￥2480 In stock
25 mg ￥4280 In stock
50 mg ￥7280 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Azenosertib (ZN-c3, Wee1 inhibitor ZN-c33) is a highly potent, selective Wee1 inhibitor with IC50 of 3.8 nM.
ZN-c3 showed excellent in vivo efficacy and is currently being evaluated in phase 2 clinical trials.

物理化学性质&存储条件

分子量 526.645
分子式 C29H34N8O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-2-allyl-1-(7-ethyl-7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)-6-((4-(4-methylpiperazin-1-yl)phenyl)amino)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one

参考文献

1. Peter Q Huang, et al. J Med Chem. 2021 Sep 9;64(17):13004-13024.

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