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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-Azathramycin
Azathramycin

Chemical Structure : Azathramycin

CAS No.: 76801-85-9

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Azathramycin (Azaerythromycin A, Desmethyl Azithromycin)

货号: PC-45263Not For Human Use, Lab Use Only.

Azathramycin is a macrolide antibiotic that effectively inhibits tumor angiogenesis by suppressing VEGFR2-mediated signaling pathways in lung cancer.

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50 mg ￥480 In stock
100 mg ￥680 In stock
500 mg ￥1280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Azathramycin is a macrolide antibiotic that effectively inhibits tumor angiogenesis by suppressing VEGFR2-mediated signaling pathways in lung cancer.
Azathramycin enhances paclitaxel and cisplatin in non-small cell lung cancer.

物理化学性质&存储条件

分子量 734.9579
分子式 C37H70N2O12
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,1

参考文献

1. Li F, et al. Oncol Lett. 2017 Jul;14(1):89-96.

2. Chu DJ, et al. Genet Mol Res. 2014 Apr 14;13(2):2796-805.

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