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首页-小分子抑制剂&激动剂-Others-Human Antigen R (HuR)-Azaphilone-9
Azaphilone-9

Chemical Structure : Azaphilone-9

CAS No.: 1448460-87-4

Azaphilone-9 (AZA-9)

货号: PC-60914Not For Human Use, Lab Use Only.

Azaphilone-9 is a fungal natural product that binds to HuR and inhibits HuR-RNA interaction in vitro with IC50 of 1.2 uM.

规格 价格 库存 数量
25 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Azaphilone-9 is a fungal natural product that binds to HuR and inhibits HuR-RNA interaction in vitro with IC50 of 1.2 uM.
    Azaphilone-9 inhibits HuR-AU-rich elements (ARE) interaction and blocks key RNA-binding residues of HuR.

    物理化学性质&存储条件

    分子量 435.314
    分子式 C21H23BrO5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    5-bromo-3-((S,1E,3E)-3,5-dimethylhepta-1,3-dien-1-yl)-7-methyl-6,8-dioxo-7,8-dihydro-6H-isochromen-7-yl acetate

    参考文献

    1. Kaur K, et al. PLoS One. 2017 Apr 17;12(4):e0175471.

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