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首页-小分子抑制剂&激动剂-Others-Other Targets-Azalanstat
Azalanstat

Chemical Structure : Azalanstat

CAS No.: 143393-27-5

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Azalanstat (RS-21607, RS21607)

货号: PC-23068Not For Human Use, Lab Use Only.

Azalanstat (RS-21607) is a selective cytochrome P450 enzyme lanosterol 14 alpha-demethylase cytochrome P450 enzyme lanosterol 14 alpha-demethylase (LDM), inhibits heme oxygenase 1 (HO-1, IC50=5.3 uM), shows cholesterol-lowering activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Azalanstat (RS-21607) is a selective cytochrome P450 enzyme lanosterol 14 alpha-demethylase cytochrome P450 enzyme lanosterol 14 alpha-demethylase (LDM), inhibits heme oxygenase 1 (HO-1, IC50=5.3 uM), shows cholesterol-lowering activity.

物理化学性质&存储条件

分子量 429.96
分子式 C22H24ClN3O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-[[(2S,4S)-2-[2-(4-chlorophenyl)ethyl]-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methylsulfanyl]aniline

参考文献

1. Walker KA, et al. J Med Chem. 1993 Jul 23;36(15):2235-7.

2. Burton PM, et al. Biochem Pharmacol. 1995 Aug 8;50(4):529-44.

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