Azadiradione

Chemical Structure : Azadiradione

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货号: PC-27695Not For Human Use, Lab Use Only.

Azadiradione is a tetranortriterpenoid from Azadirachta indica, directly interacts with purified human heat shock factor 1 (HSF1) with high specificity, potentiates HSF1 DNA binding activity, activates HSF1 and its target heat shock chaperone genes.

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生物&药学活性

Azadiradione is a tetranortriterpenoid from Azadirachta indica, directly interacts with purified human heat shock factor 1 (HSF1) with high specificity, potentiates HSF1 DNA binding activity, activates HSF1 and its target heat shock chaperone genes.

物理化学性质&存储条件

分子量	450.58
分子式	C28H34O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(5R,7R,8R,9R,10R,13S,17R)-17-(Furan-3-yl)-4,4,8,10,13-pentamethyl-3,16-dioxo-4,5,6,7,8,9,10,11,12,13,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-7-yl acetate

参考文献

1. Siddiqui S, et al. J Nat Prod. 1992 Mar;55(3):303-10.

2. Govindachari TR, et al. Fitoterapia. 2000 Jun;71(3):317-20.

3. Nelson VK, et al. Oncotarget. 2016 Nov 29;7(48):78281-78296.

Azadiradione

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物理化学性质&存储条件

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Azadiradione

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物理化学性质&存储条件

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