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首页-小分子抑制剂&激动剂-GPCR-Glucagon Receptor-Avexitide
Avexitide

Chemical Structure : Avexitide

CAS No.: 133514-43-9

Avexitide (Exendin(9-39) amide, Exendin 9-39 amide)

货号: PC-23574Not For Human Use, Lab Use Only.

Avexitide (Exendin-(9-39)) is a selective glucagon-like peptide 1 receptor (GLP-1R) antagonist, competes with endogenous GLP-1 for binding to GLP-1 receptors with Ki of 4.0 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Avexitide (Exendin-(9-39)) is a selective glucagon-like peptide 1 receptor (GLP-1R) antagonist, competes with endogenous GLP-1 for binding to GLP-1 receptors with Ki of 4.0 nM.

物理化学性质&存储条件

分子量 3369.8
分子式 C149H234N40O47S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

参考文献

1. Tan M, et al. Diabetes Obes Metab. 2020 Aug;22(8):1406-1416.

2. Schepp W, et al. Eur J Pharmacol. 1994 Oct 14;269(2):183-91.

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