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首页-抗体和重组蛋白-Biosimilar Antibody-Avelumab
Avelumab

Chemical Structure : Avelumab

CAS No.: 1537032-82-8

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Avelumab (Anti-human PD-L1 mAb, human IgG1-Lambda)

货号: PC-Ab1005Not For Human Use, Lab Use Only.

Avelumab is a fully human IgG1 anti-PD-L1 mAb to programmed cell death receptor ligand 1 (PD-L1), which modulates T cell immune reactivity and is used in the immunotherapy of cancer. Avelumab has major side effects and particularly immune related conditions, including acute liver injury which can be serious and even life threatening..

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1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Avelumab is a fully human IgG1 anti-PD-L1 mAb to programmed cell death receptor ligand 1 (PD-L1), which modulates T cell immune reactivity and is used in the immunotherapy of cancer. Avelumab has major side effects and particularly immune related conditions, including acute liver injury which can be serious and even life threatening.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Lambda
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Avelumab; MSB0010718C; Bavencio; programmed death-1; programmed death 1; PD1; PD 1; Programmed cell death protein 1; hPD-1; hPD1; hPD 1; hPD-L1;PD-L1

参考文献

1. 1, Powles T, et al. N Engl J Med. 2020 Sep 24;383(13):1218-1230. 2, Motzer RJ, et al. N Engl J Med. 2019 Mar 21;380(12):1103-1115. 3, Boyerinas B, et al. Cancer Immunol Res. 2015 Oct;3(10):1148-1157. 4, Juliá EP, et al. Front Immunol. 2018 Sep 20;9:2140.

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