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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Thrombopoietin Receptor (CD110)-Avatrombopag
Avatrombopag

Chemical Structure : Avatrombopag

CAS No.: 570406-98-3

Avatrombopag (AKR-501, E5501, YM477)

货号: PC-22882Not For Human Use, Lab Use Only.

Avatrombopag (AKR-501, YM477) is a potent, orally active, nonpeptide thrombopoietin (TPO) receptor agonist with EC50 of 3.3 nM, mimics the biological activities of TPO.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Avatrombopag (AKR-501, YM477) is a potent, orally active, nonpeptide thrombopoietin (TPO) receptor agonist with EC50 of 3.3 nM, mimics the biological activities of TPO.

物理化学性质&存储条件

分子量 649.65
分子式 C29H34Cl2N6O3S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid

参考文献

1. Fukushima-Shintani M, et al. Eur J Haematol. 2009;82(4):247-254.

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