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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phosphodiesterase (PDE)-Avanafil
Avanafil

Chemical Structure : Avanafil

CAS No.: 330784-47-9

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Avanafil (TA1790, TA-1790)

货号: PC-45440Not For Human Use, Lab Use Only.

Avanafil (TA1790) is a potent and highly selective PDE5 inhibitor (IC50=5.2 nM) for erectile dysfunction.

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250 mg ￥880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Avanafil (TA1790) is a potent and highly selective PDE5 inhibitor (IC50=5.2 nM) for erectile dysfunction.
Avanafil (TA1790)  shows no significant effect on PDE1, PDE6 and PDE11.

物理化学性质&存储条件

分子量 483.9507
分子式 C23H26ClN7O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-

参考文献

1. Kotera J, et al. J Urol. 2012 Aug;188(2):668-74.

2. Limin M, et al. Expert Opin Investig Drugs. 2010 Nov;19(11):1427-37.

3. Wang R, et al. J Sex Med. 2012 Aug;9(8):2122-9.

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