Asarinin

Chemical Structure : Asarinin

CAS No.: 133-05-1

加入收藏

货号: PC-27896Not For Human Use, Lab Use Only.

规格	价格	库存
25 mg	￥880	In stock
50 mg	￥1280	In stock
100 mg	￥1980	In stock
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Asarinin is an abundant and characteristic lignan in Asarum with significant anti-inflammatory effects, prolongs allograft survival and inhibits post-transplant immune rejection via TLR-MyD88 signaling pathway, also exerts pro-apoptotic effects in MC cells by modulating the STAT3 signaling pathway.
Asarinin inhibited TGF-β1-induced fibroblast-to-myofibroblast transition in vitro, while GW9662 and PPARγ gene silencing significantly inhibited this effect.
Asarinin inhibited not only the canonical Smad pathway of TGF-β but also the non-canonical AKT and MAPK pathways by activating PPARγ.
Asarinin attenuates ferroptosis resistance by inhibiting the activity of S-adenosyl homocysteine hydrolase in lung cancer.

物理化学性质&存储条件

分子量	354.36
分子式	C20H18O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	rel-(1R,3aR,4S,6aR)-1,4-Bis(benzo[d][1,3]dioxol-5-yl)tetrahydro-1H,3H-furo[3,4-c]furan

参考文献

1. Rushendran R, et al. Sci Rep. 2024 Aug 30;14(1):20207.

2. Zhang L, et al. Transpl Immunol. 2023 Dec;81:101949.

3. Zeng Q, et al. Sci Rep. 2023 Sep 7;13(1):14706.

4. Gu J, et al. Transplant Proc. 2015 Mar;47(2):545-8.

Asarinin

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Asarinin

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.