Asaretoclax | BCL-2 inhibitor | Probechem Biochemicals

Chemical Structure : Asaretoclax

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Asaretoclax (ZN-d5)

货号: PC-24935Not For Human Use, Lab Use Only.

Asaretoclax (ZN-d5) is a potent, selective and orally bioavailable inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2), with potential pro-apoptotic and antineoplastic activities.

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生物&药学活性

Asaretoclax (ZN-d5) is a potent, selective and orally bioavailable inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2), with potential pro-apoptotic and antineoplastic activities.

物理化学性质&存储条件

分子量	902.07
分子式	C47H57F2N7O7S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzamide, 4-[4-[[2-[3-(difluoromethyl)bicyclo[1.1.1]pent-1-yl]-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(trans-4-hydroxy-4-methylcyclohexyl)methyl]amino]-3-nitrophenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-

参考文献

1. Patent WO2022133446 A1.

Asaretoclax (ZN-d5)

生物&药学活性

物理化学性质&存储条件

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Asaretoclax (ZN-d5)

生物&药学活性

物理化学性质&存储条件

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