欢迎访问ProbeChem中文网站,英文网站请访问www.probechem.com

首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Heat Shock Protein (HSP)-Arimoclomol maleate
Arimoclomol maleate

Chemical Structure : Arimoclomol maleate

CAS No.: 289893-26-1

Arimoclomol maleate (BRX-220, BRX220)

货号: PC-60545Not For Human Use, Lab Use Only.

Arimoclomol maleate (BRX-220) is a nontoxic, orally active heat shock protein (HSP) coinducer and potentiator of the heat shock response.

规格 价格 库存 数量
5 mg ¥880 In stock
10 mg ¥1280 In stock
25 mg ¥2180 In stock
50 mg Get quote
100 mg Get quote

大包装,大折扣!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Arimoclomol maleate (BRX-220) is a nontoxic, orally active heat shock protein (HSP) coinducer and potentiator of the heat shock response.
Arimoclomol maleate (BRX-220) significantly increases pancreatic levels of HSP60 and HSP72 in vivo, significantly delays disease progression and prevents protein aggregation in the SOD1 mouse model of ALS.

物理化学性质&存储条件

分子量 429.854
分子式 C18H24ClN3O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Pyridinecarboximidoyl chloride, N-[(2R)-2-hydroxy-3-(1-piperidinyl)propoxy]-, 1-oxide, (2Z)-2-butenedioate (1:1) (salt) (9CI)

参考文献

1. Kieran D, et al. Nat Med. 2004 Apr;10(4):402-5.

2. Parfitt DA, et al. Cell Death Dis. 2014 May 22;5:e1236.

3. Rakonczay Z Jr, et al. Free Radic Biol Med. 2002 Jun 15;32(12):1283-92.

4. Kalmar B, et al. J Neurochem. 2008 Oct;107(2):339-50.

备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: