Arimoclomol (BRX-220) | HSP inducer | Probechem Biochemicals

Chemical Structure : Arimoclomol

CAS No.: 289893-25-0

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Arimoclomol (BRX-220, BRX 220, BRX220)

货号: PC-60544Not For Human Use, Lab Use Only.

Arimoclomol (BRX-220) is a nontoxic heat shock protein (HSP) coinducer and potentiator of the heat shock response.

规格	价格	库存
5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

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生物&药学活性

Arimoclomol (BRX-220) is a nontoxic heat shock protein (HSP) coinducer and potentiator of the heat shock response.
Arimoclomol (BRX-220) significantly increases pancreatic levels of HSP60 and HSP72 in vivo, significantly delays disease progression and prevents protein aggregation in the SOD1 mouse model of ALS.

物理化学性质&存储条件

分子量	313.782
分子式	C14H20ClN3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R,Z)-3-(chloro((2-hydroxy-3-(piperidin-1-yl)propoxy)imino)methyl)pyridine 1-oxide

参考文献

1. Kieran D, et al. Nat Med. 2004 Apr;10(4):402-5.

2. Parfitt DA, et al. Cell Death Dis. 2014 May 22;5:e1236.

3. Rakonczay Z Jr, et al. Free Radic Biol Med. 2002 Jun 15;32(12):1283-92.

4. Kalmar B, et al. J Neurochem. 2008 Oct;107(2):339-50.

Arimoclomol (BRX-220, BRX 220, BRX220)

生物&药学活性

物理化学性质&存储条件

参考文献

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Arimoclomol (BRX-220, BRX 220, BRX220)

生物&药学活性

物理化学性质&存储条件

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