Chemical Structure : Aprutumab
CAS No.: 1634620-63-5
货号: PC-Ab1050Not For Human Use, Lab Use Only.
Aprutumab Ixadotin (BAY 1187982) is an antibody-drug conjugate (ADC) directed against the fibroblast growth factor receptor type 2 (FGFR2) and conjugated to an as of yet unidentified toxin, with potential antineoplastic activity. Aprutumab is a fully human FGFR2 monoclonal antibody (mAb BAY 1179470), which binds to the FGFR2 isoforms FGFR2-IIIb and FGFR2-IIIc, conjugated through a noncleavable linker to a novel derivative of the microtubule-disrupting cytotoxic drug auristatin (FGFR2-ADC)..
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Aprutumab Ixadotin (BAY 1187982) is an antibody-drug conjugate (ADC) directed against the fibroblast growth factor receptor type 2 (FGFR2) and conjugated to an as of yet unidentified toxin, with potential antineoplastic activity. Aprutumab is a fully human FGFR2 monoclonal antibody (mAb BAY 1179470), which binds to the FGFR2 isoforms FGFR2-IIIb and FGFR2-IIIc, conjugated through a noncleavable linker to a novel derivative of the microtubule-disrupting cytotoxic drug auristatin (FGFR2-ADC).
分子量 | ||
分子式 | Human IgG1-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Aprutumab; BAY-1179470; BAY 1179470; Aprutumab ixadotin; BAY 1187982; 1634620-63-5; Fibroblast growth factor receptor 2; FGFR2. |
1. 1, Sommer A, et al. Cancer Res. 2016 Nov 1;76(21):6331-6339. 2, Kim SB, et al. Target Oncol. 2019 Oct;14(5):591-601.
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