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首页-抗体和重组蛋白-Biosimilar Antibody-Anti-human SIGLEC15 mAb, 5G-12
Anti-human SIGLEC15 mAb, 5G-12

Chemical Structure : Anti-human SIGLEC15 mAb, 5G-12

CAS No.:

Anti-human SIGLEC15 mAb, 5G-12 (Anti-human SIGLEC15-hIgG4P mAb, human IgG4-Kappa)

货号: PC-Ab1073Not For Human Use, Lab Use Only.

Anti-Human SIGLEC15 (5G-12) is a high affinity humanized IgG4 mAb specific for SIGLEC15 (S15, Sialic Acid-Binding Ig-Like Lectin 15), blocks Siglec-15-mediated suppression of murine OT-I responses to 293T-K b OVA-S15 + or OVA 257-264-pulsed mouse primary macrophages, inhibits the growth of established tumors in murine models..

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1 mg ¥3580 In stock
5 mg ¥7580 In stock
10 mg ¥12800 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Anti-Human SIGLEC15 (5G-12) is a high affinity humanized IgG4 mAb specific for SIGLEC15 (S15, Sialic Acid-Binding Ig-Like Lectin 15), blocks Siglec-15-mediated suppression of murine OT-I responses to 293T-K b OVA-S15 + or OVA 257-264-pulsed mouse primary macrophages, inhibits the growth of established tumors in murine models.

物理化学性质&存储条件

分子量
分子式 Human IgG4-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

Anti-Human SIGLEC15 5G-12; human Siglec-15 protein; CD33 Antigen-Like 3, CD33L3, Sialic Acid-Binding Ig-Like Lectin 15, SIGLEC-15, HsT1361, CD33 Molecule-Like 3, Sialic Acid Binding Ig-Like Lectin 15; anti-human S15; α-S15

参考文献

1. 1, Jun Wang, et al. Nat Med. 2019 Apr;25(4):656-666.

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