Ansamitocin P-3 |CAS:66547-09-9 Probechem Biochemicals

Chemical Structure : Ansamitocin P-3

CAS No.: 66547-09-9

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Ansamitocin P-3 (Maytansinol butyrate)

货号: PC-45742Not For Human Use, Lab Use Only.

A microtubule depolymerizing agent that can be isolated from culture broths of certain Gram-positive bacteria.

规格	价格	库存
10 mg	￥1680	In stock
50 mg	￥3920	In stock
100 mg	￥5200	In stock

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生物&药学活性

A microtubule depolymerizing agent that can be isolated from culture broths of certain Gram-positive bacteria; binds tubulin (Kd=1.3 uM), depolymerizes microtubules in both interphase and mitosis, and perturbs chromosome segregation; inhibits the growth of cancer cells in culture and significantly suppresses the growth of several cancer tumors in mice.

物理化学性质&存储条件

分子量	635.1448
分子式	C32H43ClN2O9
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Maytansine, 3-O-de[2-(acetylmethylamino)-1-oxopropyl]-3-O-(1-oxobutyl)-

参考文献

1. Ootsu K, et al. Cancer Res. 1980 May;40(5):1707-17.

2. Venghateri JB, et al. PLoS One. 2013 Oct 4;8(10):e75182.

3. Martin K, et al. Cancer Immunol Immunother. 2014 Sep;63(9):925-38.

Ansamitocin P-3 (Maytansinol butyrate)

生物&药学活性

物理化学性质&存储条件

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Ansamitocin P-3 (Maytansinol butyrate)

生物&药学活性

物理化学性质&存储条件

参考文献

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