Anle-138b |CAS:882697-00-9 Probechem Biochemicals

Chemical Structure : Anle-138b

CAS No.: 882697-00-9

加入收藏

Anle-138b (Anle138b, Emrusolmin)

货号: PC-70278Not For Human Use, Lab Use Only.

Emrusolmin (Anle-138b) is a novel oligomer modulator that blocks the formation of pathological aggregates of prion protein (PrP(Sc)) and of α-synuclein (α-syn).

规格	价格	库存
10 mg	￥780	In stock
25 mg	￥1280	In stock
50 mg	￥1980	In stock
100 mg	￥3280	In stock
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Emrusolmin (Anle-138b) is a novel oligomer modulator that blocks the formation of pathological aggregates of prion protein (PrP(Sc)) and of α-synuclein (α-syn).
Emrusolmin (Anle-138b) strongly inhibits all prion strains tested including BSE-derived and human prions.
Emrusolmin (Anle-138b) binds to aggregated tau and inhibits tau aggregation in vitro and in vivo.
Emrusolmin (Anle-138b) has no detectable toxicity, excellent oral bioavailability and blood-brain-barrier penetration.

物理化学性质&存储条件

分子量	343.17
分子式	C16H11BrN2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(1,3-Benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole

参考文献

1. Turriani E, et al. Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):E4971-E4977.

2. Wagner J, et al. Acta Neuropathol. 2013 Jun;125(6):795-813.

3. Wagner J, et al. Acta Neuropathol. 2015 Nov;130(5):619-31.

Anle-138b (Anle138b, Emrusolmin)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Anle-138b (Anle138b, Emrusolmin)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.