Aniracetam | AMPAR PAM | Probechem Biochemicals

Chemical Structure : Aniracetam

CAS No.: 72432-10-1

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Aniracetam (Ro 13-5057, Ro13-5057)

货号: PC-42742Not For Human Use, Lab Use Only.

Aniracetam (Ro 13-5057) is a positive allosteric modulator of AMPAR, potentiates the iQA responses induced in Xenopus oocytes by rat brain mRNA in a reversible manner.

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生物&药学活性

Aniracetam (Ro 13-5057) is a positive allosteric modulator of AMPAR, potentiates the iQA responses induced in Xenopus oocytes by rat brain mRNA in a reversible manner.
Aniracetam enhances glutamate-evoked currents in whole-cell recordings.
Aniracetam strongly reduces glutamate receptor desensitization.
Aniracetam selectively prolongs the time course and increases the peak amplitude of fast synaptic currents.

物理化学性质&存储条件

分子量	219.2365
分子式	C12H13NO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Pyrrolidinone, 1-(4-methoxybenzoyl)-

参考文献

1. Ito I, et al. J Physiol. 1990 May;424:533-43.

2. Isaacson JS, et al. Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10936-40.

3. Tang CM, et al. Science. 1991 Oct 11;254(5029):288-90.

Aniracetam (Ro 13-5057, Ro13-5057)

生物&药学活性

物理化学性质&存储条件

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Aniracetam (Ro 13-5057, Ro13-5057)

生物&药学活性

物理化学性质&存储条件

参考文献

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