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首页-小分子抑制剂&激动剂-GPCR-Ghrelin Receptor (GHSR)-Anamorelin fumarate
Anamorelin fumarate

Chemical Structure : Anamorelin fumarate

CAS No.: 339539-92-3

Anamorelin fumarate (RC1291 Fumarate, ONO7643 Fumarate)

货号: PC-44045Not For Human Use, Lab Use Only.

Anamorelin fumarate (RC-1291, ONO-7643) is a non-peptide, centrally-penetrant and selective agonist of GHSR with 50 of 0.74 nM, shows appetite-enhancing and anabolic effects, orally bioactive.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Anamorelin fumarate (RC-1291, ONO-7643) is a non-peptide, centrally-penetrant and selective agonist of GHSR with 50 of 0.74 nM, shows appetite-enhancing and anabolic effects, orally bioactive.

物理化学性质&存储条件

分子量 662.7758
分子式 C35H46N6O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Piperidinecarboxylic acid, 1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-, trimethylhydrazide, (3R)-, (2E)-2-butenedioate (1:1) (9CI)

参考文献

1. Northrup R, et al. Support Care Cancer. 2013 Sep;21(9):2409-15.

2. Zhang H, et al. Expert Opin Pharmacother. 2015 Jun;16(8):1245-53.

3. Pietra C, et al. J Cachexia Sarcopenia Muscle. 2014 Dec;5(4):329-37.

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