Anacetrapib (MK-0859) | CETP inhibitor | Probechem Biochemicals

Chemical Structure : Anacetrapib

CAS No.: 875446-37-0

加入收藏

Anacetrapib (MK-0859, MK0859)

货号: PC-42893Not For Human Use, Lab Use Only.

Anacetrapib (MK 0859) is a potent, orally active cholesteryl ester transfer protein (CETP) inhibitor with IC50 of 7.9 nM and 11.8 nM for rhCETP and C13S CETP mutant, respectively.

规格	价格	库存
10 mg	￥980	In stock
25 mg	￥1580	In stock
50 mg	￥2580	In stock
100 mg	￥4280	In stock
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Anacetrapib (MK-0859) is a potent, orally active cholesteryl ester transfer protein (CETP) inhibitor with IC50 of 7.9 nM and 11.8 nM for rhCETP and C13S CETP mutant, respectively.
Anacetrapib (MK-0859) inhibits CETP-mediated cholesterol exchange, resulting in elevated HDL-cholesterol levels and reductions in LDL-cholesterol levels.
Anacetrapib (MK-0859) demonstrates potential to treat elevated cholesterol levels in an effort prevent cardiovascular disease.

物理化学性质&存储条件

分子量	637.5084
分子式	C30H25F10NO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Oxazolidinone, 5-[3,5-bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-2'-methoxy-5'-(1-methylethyl)-4-(trifluoromethyl)[1,1'-biphenyl]-2-yl]methyl]-4-methyl-, (4S,5R)-

参考文献

1. Krishna R, et al. Lancet. 2007 Dec 8;370(9603):1907-14.

2. Vergeer M, et al. Nat Clin Pract Cardiovasc Med. 2008 Jun;5(6):302-3.

3. Cannon CP, et al. Am Heart J. 2009 Oct;158(4):513-519.e3.

4. Niesor EJ, et al. J Lipid Res. 2010 Dec;51(12):3443-54.

Anacetrapib (MK-0859, MK0859)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Anacetrapib (MK-0859, MK0859)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.