Amprenavir |CAS:161814-49-9 Probechem Biochemicals

Chemical Structure : Amprenavir

CAS No.: 161814-49-9

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Amprenavir (VX-478;141W94;VX478)

货号: PC-45253Not For Human Use, Lab Use Only.

Amprenavir (VX-478) is a potent HIV-1 protease inhibitor with IC50 of 80 nM, has mean IC50 of 12 nM against 6 HIV clinical isolates.

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25 mg	￥1180	In stock
50 mg	￥1780	In stock
100 mg	￥2780	In stock
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1 g		Get quote

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生物&药学活性

Amprenavir (VX-478) is a potent HIV-1 protease inhibitor with IC50 of 80 nM, has mean IC50 of 12 nM against 6 HIV clinical isolates.
Amprenavir (VX-478) shows synergistic effect with a variety of anti-HIV-1 agents and exhibits a unique cross resistance profile.

物理化学性质&存储条件

分子量	505.6269
分子式	C25H35N3O6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3S)-tetrahydro-3-furanyl ester

参考文献

1. St Clair MH, et al. Antiviral Res. 1996 Jan;29(1):53-6.

2. Partaledis JA, et al. J Virol. 1995 Sep;69(9):5228-35.

3. Markland W, et al. J Virol. 2000 Aug;74(16):7636-41.

Amprenavir (VX-478;141W94;VX478)

生物&药学活性

物理化学性质&存储条件

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Amprenavir (VX-478;141W94;VX478)

生物&药学活性

物理化学性质&存储条件

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