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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-Amisulpride
Amisulpride

Chemical Structure : Amisulpride

CAS No.: 71675-85-9

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Amisulpride (SEP-4199, DAN2163, DAN 2163)

货号: PC-23210Not For Human Use, Lab Use Only.

Amisulpride (SEP-4199, DAN2163) is an N-methylated analogue of amisulpride, selective dopamine D(2/3)/5-HT(7) inhibitor, binds to the D2 receptor and 5-HT7 receptor with Ki of 1.1 nM and 44 nM respectively, shows potential for treatment of schizophrenia and other psychiatric disorders.

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100 mg ￥880 In stock
250 mg ￥1380 In stock
500 mg ￥2180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Amisulpride (SEP-4199, DAN2163) is an N-methylated analogue of amisulpride, selective dopamine D(2/3)/5-HT(7) inhibitor, binds to the D2 receptor and 5-HT7 receptor with Ki of 1.1 nM and 44 nM respectively, shows potential for treatment of schizophrenia and other psychiatric disorders.

物理化学性质&存储条件

分子量 369.48
分子式 C17H27N3O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-amino-N-((1-ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide

参考文献

1. Biernat L, et al. Psychopharmacology (Berl). 2022 Sep;239(9):3009-3018.

2. Grattan V, et al. ACS Omega. 2019 Aug 15;4(9):14151-14154.

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