Aminopyridine 2 | MPO inhibitor | Probechem Biochemicals

Chemical Structure : Aminopyridine 2

加入收藏

Aminopyridine 2 (MPO inhibitor AP-2)

货号: PC-35561Not For Human Use, Lab Use Only.

Aminopyridine 2 (MPO inhibitor AP-2) is a novel potent, selective, orally available inhibitor of Myeloperoxidase (MPO), inhibits MPO peroxidase activity in vitro and in human plasma with IC50 of 0.16 and 1.9 uM, respectively.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Aminopyridine 2 (MPO inhibitor AP-2) is a novel potent, selective, orally available inhibitor of Myeloperoxidase (MPO), inhibits MPO peroxidase activity in vitro and in human plasma with IC50 of 0.16 and 1.9 uM, respectively.
Aminopyridine 2 also inhibits eosinophil peroxidase (EPO, IC50=0.29 uM), and shows no apparent activity against other oxidases.
Aminopyridine 2 blockes MPO-dependent vasomotor dysfunction ex vivo in rat aortic rings, also inhibits MPO activity in vivo in a mouse model of peritonitis.

物理化学性质&存储条件

分子量	321.178
分子式	C13H13BrN4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-((6-aminopyridin-3-yl)methyl)-3-(4-bromophenyl)urea

参考文献

1. Marro ML, et al. J Pharmacol Exp Ther. 2018 Aug 3. pii: jpet.118.248435.

Aminopyridine 2 (MPO inhibitor AP-2)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Aminopyridine 2 (MPO inhibitor AP-2)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.