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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Sodium Channel-Amiloride
Amiloride

Chemical Structure : Amiloride

CAS No.: 2609-46-3

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Amiloride (MK-870, MK870)

货号: PC-23672Not For Human Use, Lab Use Only.

Amiloride (MK-870) is an inhibitor of both epithelial sodium channel (ENaC and urokinase-type plasminogen activator receptor (uTPA), also is a blocker of polycystin-2 (PC2, TRPP2) channel.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Amiloride (MK-870) is an inhibitor of both epithelial sodium channel (ENaC and urokinase-type plasminogen activator receptor (uTPA), also is a blocker of polycystin-2 (PC2, TRPP2) channel.

物理化学性质&存储条件

分子量 229.63
分子式 C6H8ClN7O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide

参考文献

1. Ji, H.L., et al. Am J Physiol Lung Cell Mol Physiol, 2012. 303(12): p. L1013-2

2. Giamarchi A, et al. EMBO J. 2010 Apr 7;29(7):1176-91.

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