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首页-小分子抑制剂&激动剂-GPCR-Endothelin Receptor-Ambrisentan
Ambrisentan

Chemical Structure : Ambrisentan

CAS No.: 177036-94-1

Ambrisentan (BSF208075, BSF-208075, LU208075, LU-208075)

货号: PC-43394Not For Human Use, Lab Use Only.

Ambrisentan (BSF 208075, LU 208075) is a highly selective antagonist of the endothelin-1 type A receptor (ETA) for use in the treatment of pulmonary hypertension.

规格 价格 库存 数量
25 mg ¥880 In stock
100 mg ¥1580 In stock
500 mg ¥2880 In stock
1 g ¥3980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ambrisentan (BSF 208075, LU 208075) is a highly selective antagonist of the endothelin-1 type A receptor (ETA) for use in the treatment of pulmonary hypertension.

物理化学性质&存储条件

分子量 378.4211
分子式 C22H22N2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzenepropanoic acid, .alpha.-[(4,6-dimethyl-2-pyrimidinyl)oxy]-.beta.-methoxy-.beta.-phenyl-, (.alpha.S)-

参考文献

1. Gäbel G, et al. Transplant Proc. 2003 Sep;35(6):2137-8.

2. Witzigmann H, et al. Transplant Proc. 2002 Sep;34(6):2387-8.

3. Vatter H, et al. Cardiovasc Drug Rev. 2006 Spring;24(1):63-76.

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