Chemical Structure : Amatuximab
CAS No.: 931402-35-6
货号: PC-Ab1080Not For Human Use, Lab Use Only.
Mesothelin (MSLN) is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Amatuximab (MORAb-009) blocks the binding of mesothelin to CA 125 and thus could be used also as a strategy to prevent tumor metastasis..
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Mesothelin (MSLN) is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Amatuximab (MORAb-009) blocks the binding of mesothelin to CA 125 and thus could be used also as a strategy to prevent tumor metastasis.
分子量 | ||
分子式 | Human IgG1-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Amatuximab; MORAb-009; MORAb009; 931402-35-6; anti human MSLN; anti human Mesothelin |
1. 1, Nicolaides NC, et al. Cancer Biol Ther. 2018 Jul 3;19(7):622-630. 2, Hassan R, et al. Cancer Immun. 2007 Dec 19;7:20. 3, Hassan R, et al. Clin Cancer Res. 2010 Dec 15;16(24):6132-8. 4, Shin IS, et al. Nucl Med Biol. 2011 Nov;38(8):1119-27.
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