Alvimopan monohydrate |CAS:1383577-62-5 Probechem Biochemicals

Chemical Structure : Alvimopan monohydrate

CAS No.: 1383577-62-5

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Alvimopan monohydrate

货号: PC-45976Not For Human Use, Lab Use Only.

A selective peripherally acting μ-opioid antagonist with IC50 of 1.7 nM for the treatment of postoperative ileus.

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10 mg	￥1936.0	In stock
50 mg	￥5720	In stock
250 mg		Get quote

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生物&药学活性

A selective peripherally acting μ-opioid antagonist with IC50 of 1.7 nM for the treatment of postoperative ileus; prevents gastrointestinal effects of intravenous morphine without affecting analgesia; orally active.

Other Indication

Approved

物理化学性质&存储条件

分子量	442.5479
分子式	C25H34N2O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Glycine, N-[(2S)-2-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]-, hydrate (1:1)

参考文献

1. Fukuda H, et al. Brain Res. 2006 Aug 2;1102(1):63-70.

2. Taguchi A, et al. N Engl J Med. 2001 Sep 27;345(13):935-40.

3. Schmidt WK. Am J Surg. 2001 Nov;182(5A Suppl):27S-38S.

Alvimopan monohydrate

生物&药学活性

物理化学性质&存储条件

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Alvimopan monohydrate

生物&药学活性

物理化学性质&存储条件

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