Aloxistatin |CAS:88321-09-9 Probechem Biochemicals

Chemical Structure : Aloxistatin

CAS No.: 88321-09-9

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Aloxistatin (E64d, E64c ethyl ester, Loxistatin, Rexostatine)

货号: PC-42094Not For Human Use, Lab Use Only.

Aloxistatin (E64d) is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with the ability to inhibit calpain activity in intact platelets.

规格	价格	库存
5 mg	￥880	In stock
10 mg	￥1380	In stock
25 mg	￥2280	In stock
50 mg	￥3880	In stock
100 mg		Get quote

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生物&药学活性

Aloxistatin (E64d) is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with the ability to inhibit calpain activity in intact platelets.
Aloxistatin (E64d) reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B.

物理化学性质&存储条件

分子量	342.4305
分子式	C17H30N2O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 23 mg/mL
Chemical Name/SMILES	2-Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, ethyl ester, (2S,3S)-

参考文献

1. Ostrowski LE, et al. Cancer Res. 1986 Aug;46(8):4121-8.

2. Hook G, et al. J Alzheimers Dis. 2011;26(2):387-408.

3. McGowan EB, et al. Biochem Biophys Res Commun. 1989 Jan 31;158(2):432-5.

Aloxistatin (E64d, E64c ethyl ester, Loxistatin, Rexostatine)

生物&药学活性

物理化学性质&存储条件

参考文献

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Aloxistatin (E64d, E64c ethyl ester, Loxistatin, Rexostatine)

生物&药学活性

物理化学性质&存储条件

参考文献

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