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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Dipeptidyl Peptidase (DPP)-Alogliptin benzoate
Alogliptin benzoate

Chemical Structure : Alogliptin benzoate

CAS No.: 850649-62-6

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Alogliptin benzoate (SYR 322)

货号: PC-23797Not For Human Use, Lab Use Only.

Alogliptin benzoate (SYR-322) is a potent, selective and orally active inhibitor of DPP-4 with IC50 of <10 nM, >10,000-fold selectivity over DPP-8 and DPP-9.

规格 价格 库存 数量
25 mg ￥880 In stock
100 mg ￥1480 In stock
250 mg ￥2480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Alogliptin benzoate (SYR-322) is a potent, selective and orally active inhibitor of DPP-4 with IC50 of <10 nM, >10,000-fold selectivity over DPP-8 and DPP-9.

物理化学性质&存储条件

分子量 461.52
分子式 C25H27N5O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile benzoate

参考文献

1. Feng J, et al. J Med Chem. 2007 May 17;50(10):2297-300.

2. Thomas L, et al. J Pharmacol Exp Ther. 2008 Apr;325(1):175-82.

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