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首页-抗体和重组蛋白-Biosimilar Antibody-Alnuctamab
Alnuctamab

Chemical Structure : Alnuctamab

CAS No.: 2296827-07-9

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Alnuctamab (CC-93269, Anti-TNFRSF17/CD3E mAb)

货号: PC-38851Not For Human Use, Lab Use Only.

Alnuctamab (CC-93269) is a T-cell redirecting bispecific antibody (BiTE) targeting BCMA for the treatment of multiple myeloma.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Alnuctamab (CC-93269) is a T-cell redirecting bispecific antibody (BiTE) targeting BCMA (TNFRSF17) and CD3ε for the treatment of multiple myeloma, binds bivalently to BCMA and monovalently to CD3ε in a 2+1 format.
Isotype: G1-kappa/lambda with domain crossover
Anti-[human TNFRSF17 (TNF receptor superfamily member 17, tumor necrosis factor receptor superfamily, member 17, B cell maturation antigen, BCMA, BCM, TNFRSF13A, CD269)] and anti-[human CD3E (CD3 epsilon, Leu-4)], monoclonal antibody, bispecific, trivalent.

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Verkleij CPM, et al. Oncotarget. 2020 Nov 10;11(45):4076-4081.

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