Aliskiren hemifumarate |CAS:173334-58-2 Probechem Biochemicals

Chemical Structure : Aliskiren hemifumarate

CAS No.: 173334-58-2

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货号: PC-42906Not For Human Use, Lab Use Only.

Aliskiren (CGP60536B) hemifumarate is a first-in-class, potent and highly selective, direct renin inhibitor with IC50 of 0.6 nM.

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Aliskiren (CGP60536B) hemifumarate is a first-in-class, potent and highly selective, direct renin inhibitor with IC50 of 0.6 nM.

Aliskiren shows no significant inhibition on Cathepsin D, Cathepsin E, Pepsin and HIV-1 peptidase (> 50 uM); orally bioactive.

分子量	1219.589
分子式	C64H110N6O16
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzeneoctanamide, δ-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,ζ-bis(1-methylethyl)-, (αS,γS,δS,ζS)-, (2E)-2-butenedioate (2:1)

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2. Desjarlais M, et al. Atherosclerosis. 2015 Oct;242(2):450-60.

3. Jumar A, et al. J Hypertens. 2015 Dec;33(12):2491-9.