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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aldehyde Dehydrogenase (ALDH)-Aldi-6
Aldi-6

Chemical Structure : Aldi-6

CAS No.: 2138-34-3

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Aldi-6 (Aldi6)

货号: PC-70323Not For Human Use, Lab Use Only.

Aldi-6 is a novel small molecule ALDH inhibitor with IC50 of 600 nM, 800 nM and 1000 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively.

规格 价格 库存 数量
25 mg ￥1280 In stock
50 mg ￥1880 In stock
100 mg ￥3280 In stock
200 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Aldi-6 is a novel small molecule ALDH inhibitor with IC50 of 600 nM, 800 nM and 1000 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively.
Aldi-6 decreases SCC4 cells viability, sensitizes HNSCC cells to cisplatin.
The combination of Aldi-6 and cisplatin causes a greater reduction in tumor burden in vivo than cisplatin alone.

物理化学性质&存储条件

分子量 256.143
分子式 C11H14BrNO
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(4-bromophenyl)-3-(dimethylamino)propan-1-one

参考文献

1. Kim J, et al. Oncotarget. 2017 Apr 10. doi: 10.18632/oncotarget.17017.

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