Alda-1 |CAS:349438-38-6 Probechem Biochemicals

Chemical Structure : Alda-1

CAS No.: 349438-38-6

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Alda-1 (ALDH2 activator Alda-1)

货号: PC-45563Not For Human Use, Lab Use Only.

Alda-1 is a small-molecule activator of ALDH2, particularly effective activator of ALDH2*2 (EC50= 20 uM, increases the activity of the mutant, ALDH2*2 (11-fold).

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25 mg	￥1280	In stock
50 mg	￥1980	In stock
100 mg	￥2980	In stock
200 mg		Get quote
1 g		Get quote

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生物&药学活性

Alda-1 is a small-molecule activator of ALDH2, particularly effective activator of ALDH2*2 (EC50= 20 uM, increases the activity of the mutant, ALDH2*2 (11-fold).
Alda-1 causes slight inhibition of GTN denitration and did not increase GTN-induced sGC activation in the presence of either variant; no effect on ADH1.

物理化学性质&存储条件

分子量	324.1588
分子式	C15H11Cl2NO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 51 mg/mL
Chemical Name/SMILES	Benzamide, N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichloro-

参考文献

1. Chen CH, et al. Science. 2008 Sep 12;321(5895):1493-5.

2. Beretta M, et al. J Biol Chem. 2010 Jan 8;285(2):943-52.

3. Ning S, et al. Radiat Res. 2012 Jul;178(1):69-74.

Alda-1 (ALDH2 activator Alda-1)

生物&药学活性

物理化学性质&存储条件

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Alda-1 (ALDH2 activator Alda-1)

生物&药学活性

物理化学性质&存储条件

参考文献

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