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首页-小分子抑制剂&激动剂-Others-Other Targets-Alcedaplin
Alcedaplin

Chemical Structure : Alcedaplin

CAS No.: 2956780-66-6

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Alcedaplin (MZE829, MZE-829)

货号: PC-27404Not For Human Use, Lab Use Only.

Alcedaplin (MZE829) is a small molecule inhibitor of apolipoprotein L1 (APOL1) function, blocks APOL1 pore function and ameliorate manifestations of APOL1-mediated kidney disease (AMKD).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Alcedaplin (MZE829) is a small molecule inhibitor of apolipoprotein L1 (APOL1) function, blocks APOL1 pore function and ameliorate manifestations of APOL1-mediated kidney disease (AMKD).

    物理化学性质&存储条件

    分子量 548.99
    分子式 C27H28ClF3N4O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, 5-chloro-1'-[2-[[1-(cis-3-hydroxy-3-methylcyclobutyl)-7-(trifluoromethyl)-1H-benzimidazol-5-yl]oxy]ethyl]-

    参考文献

    1. Patent WO2023141432 A2 2023-07-27.

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