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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Aryl hydrocarbon Receptor (AhR)-AhR agonist ITE
AhR agonist ITE

Chemical Structure : AhR agonist ITE

CAS No.: 448906-42-1

AhR agonist ITE (ITE)

货号: PC-45600Not For Human Use, Lab Use Only.

AhR agonist ITE is a endogenous ligand, potent aryl hydrocarbon receptor (AhR) agonist in vitro and in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AhR agonist ITE is a endogenous ligand, potent aryl hydrocarbon receptor (AhR) agonist in vitro and in vivo.
AhR agonist ITE activates the murine AhR in vivo, but does not induce toxicity.
AhR agonist ITE induces the differentiation of stem-like cancer cells and reduces their tumorigenic potential in both subcutaneous and orthotopic xenograft tumour models.

物理化学性质&存储条件

分子量 286.3058
分子式 C14H10N2O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 41 mg/mL

Chemical Name/SMILES

4-Thiazolecarboxylic acid, 2-(1H-indol-3-ylcarbonyl)-, methyl ester

参考文献

1. Henry EC, et al. Toxicol Sci. 2010 Mar;114(1):90-100.

2. Wang K, et al. Cancer Lett. 2013 Oct 28;340(1):63-71.

3. Cheng J, et al. Nat Commun. 2015 Jun 10;6:7209.

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