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AgrC inhibitor CP-20t

Chemical Structure : AgrC inhibitor CP-20t

CAS No.:

AgrC inhibitor CP-20t

货号: PC-28772Not For Human Use, Lab Use Only.

CP-20t is a potent, small molecule inhibitor of Staphylococcus aureus agr quorum sensing (QS) system with IC50 of 9.8 nM (agr group-I), acts on AgrC and blocks hemolysis of rabbit red blood cells by group-I S. aureus with IC50 of 18 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CP-20t is a potent, small molecule inhibitor of Staphylococcus aureus agr quorum sensing (QS) system with IC50 of 9.8 nM (agr group-I), acts on AgrC and blocks hemolysis of rabbit red blood cells by group-I S. aureus with IC50 of 18 nM.

物理化学性质&存储条件

分子量 440.58
分子式 C22H24N4O2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(3-(tert-butyl)phenyl)-2-(thiophene-3-carboxamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxamide

参考文献

1. A P Clay, et al. ACS Chem Biol. 2026 Nov 3:10.1021/acschembio.6c00735.

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