Agomelatine L(+)-Tartaric acid |CAS:824393-18-2 Probechem Biochemicals

Chemical Structure : Agomelatine L( )-Tartaric acid

CAS No.: 824393-18-2

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Agomelatine L( )-Tartaric acid (S-20098 L(+)-Tartaric acid)

货号: PC-45162Not For Human Use, Lab Use Only.

A melatonin receptor agonist of MT1 (Ki=0.1nM) and MT2 (Ki=0.12nM), and a 5-HT2C (Ki=631nM) receptor antagonist.

规格	价格	库存
10 mg	￥704.0	In stock
50 mg	￥2080	In stock
100 mg	￥2640	In stock

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生物&药学活性

A melatonin receptor agonist of MT1 (Ki=0.1nM) and MT2 (Ki=0.12nM), and a 5-HT2C (Ki=631nM) receptor antagonist; has no effect on monoamine uptake and no affinity for adrenergic, histaminergic, cholinergic, dopaminergic and benzodiazepine receptors, nor other serotonergic receptors; a melatonergic antidepressant treatment of major depressive disorder with relatively favorable side effect profile.

Depression

Approved

物理化学性质&存储条件

分子量	393.3878
分子式	C19H23NO8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Acetamide, N-[2-(7-methoxy-1-naphthalenyl)ethyl]- ((2R,3R)-2,3-dihydroxybutanedioate)(1:x)(9CI)

参考文献

1. Depreux P, et al. J Med Chem. 1994 Sep 30;37(20):3231-9.

2. Wiley JL, et al. Psychopharmacology (Berl). 1998 Dec;140(4):503-9.

3. Ying SW, et al. Eur J Pharmacol. 1996 Jan 18;296(1):33-42.

Agomelatine L( )-Tartaric acid (S-20098 L(+)-Tartaric acid)

生物&药学活性

物理化学性质&存储条件

参考文献

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Agomelatine L( )-Tartaric acid (S-20098 L(+)-Tartaric acid)

生物&药学活性

物理化学性质&存储条件

参考文献

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