Aducanumab |CAS:1384260-65-4 Probechem Biochemicals

Chemical Structure : Aducanumab

CAS No.: 1384260-65-4

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Aducanumab (Anti-huamn amyloid beta mAb, human IgG1(K97R)-Kappa; BIIB 037)

货号: PC-Ab1059Not For Human Use, Lab Use Only.

Aducanumab (BIIB037) is a human monoclonal antibody selectively targets aggregated Aβ, binds to the N-terminus of Aβ peptide and recognizes aggregated forms of Aβ, including epitopes or conformations present in soluble and insoluble oligomers. The FDA approved aducanumab under accelerated approval based on reduction in amyloid plaques in Alzheimer's disease (AD)..

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1 mg	￥3580	In stock
5 mg	￥7580	In stock
10 mg	￥12800	In stock
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生物&药学活性

物理化学性质&存储条件

分子量
分子式	Human IgG1(K97R)-Kappa
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES	Aducanumab; Aduhelm; anti human Amyloid beta; Beta Amyloid; Amyloid-β; anti human Aβ; BIIB 037; NI-10; 1384260-65-4

参考文献

1. 1, Sevigny J, et al. Nature. 2016 Sep 1;537(7618):50-6. 2, Ferrero J, et al. Alzheimers Dement (N Y). 2016 Jun 20;2(3):169-176. 3, Arndt JW, et al. Sci Rep. 2018 Apr 23;8(1):6412. 4, Chiao P, et al. J Nucl Med. 2019 Jan;60(1):100-106. 5, Sevigny J, et al. Nature. 2017 Jun 21;546(7659):564.

Aducanumab (Anti-huamn amyloid beta mAb, human IgG1(K97R)-Kappa; BIIB 037)

生物&药学活性

物理化学性质&存储条件

参考文献

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Aducanumab (Anti-huamn amyloid beta mAb, human IgG1(K97R)-Kappa; BIIB 037)

生物&药学活性

物理化学性质&存储条件

参考文献

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