Chemical Structure : Aducanumab
CAS No.: 1384260-65-4
货号: PC-Ab1059Not For Human Use, Lab Use Only.
Aducanumab (BIIB037) is a human monoclonal antibody selectively targets aggregated Aβ, binds to the N-terminus of Aβ peptide and recognizes aggregated forms of Aβ, including epitopes or conformations present in soluble and insoluble oligomers. The FDA approved aducanumab under accelerated approval based on reduction in amyloid plaques in Alzheimer's disease (AD)..
规格 | 价格 | 库存 | 数量 |
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1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Aducanumab (BIIB037) is a human monoclonal antibody selectively targets aggregated Aβ, binds to the N-terminus of Aβ peptide and recognizes aggregated forms of Aβ, including epitopes or conformations present in soluble and insoluble oligomers. The FDA approved aducanumab under accelerated approval based on reduction in amyloid plaques in Alzheimer's disease (AD).
分子量 | ||
分子式 | Human IgG1(K97R)-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Aducanumab; Aduhelm; anti human Amyloid beta; Beta Amyloid; Amyloid-β; anti human Aβ; BIIB 037; NI-10; 1384260-65-4 |
1. 1, Sevigny J, et al. Nature. 2016 Sep 1;537(7618):50-6. 2, Ferrero J, et al. Alzheimers Dement (N Y). 2016 Jun 20;2(3):169-176. 3, Arndt JW, et al. Sci Rep. 2018 Apr 23;8(1):6412. 4, Chiao P, et al. J Nucl Med. 2019 Jan;60(1):100-106. 5, Sevigny J, et al. Nature. 2017 Jun 21;546(7659):564.
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