AdipoR agonist Med | AdipoR agonist | Probechem Biochemicals

Chemical Structure : AdipoR agonist Med

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AdipoR agonist Med (Medicarpin sodium salt)

货号: PC-27862Not For Human Use, Lab Use Only.

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生物&药学活性

AdipoR agonist Med (Medicarpin sodium salt) is water-soluble sodium salt of Medicarpin with anticancer activity, is a dual agonist of AdipoR1 and AdipoR2, activates AdipoR1 and AdipoR2 with EC50 values of 160 and 302 pM, respectively.
AdipoR agonist Med stimulated canonical adiponectin signalling pathways, including AMPK, AKT and p38 MAPK.
AdipoR agonist Med significantly induced expression of typical adiponectin targets, PGC-1α, PPARα, Glut4 and UCP3.
AdipoR agonist Med enhanced myogenic differentiation, evidenced by increasing myotube formation and expression of MyoD, myogenin and MyHC.
AdipoR agonist Med also enhanced oxidative capacity by increasing fatty acid oxidation and Med-treated cells showed elevated oxidative fibre markers.
AdipoR agonist Med significantly attenuated muscle atrophy in rodent models of skeletal muscle atrophy.

物理化学性质&存储条件

分子量	292.27
分子式	C16H13NaO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	sodium (6aR,11aR)-9-methoxy-6a,11a-dihydro-6H-benzofuro[3,2-c]chromen-3-olate

参考文献

1. Das S, et al. J Cachexia Sarcopenia Muscle. 2026 Aug;17(4):e70364.

AdipoR agonist Med (Medicarpin sodium salt)

生物&药学活性

物理化学性质&存储条件

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AdipoR agonist Med (Medicarpin sodium salt)

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物理化学性质&存储条件

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