Chemical Structure : Adintrevimab
CAS No.: 2516243-54-0
货号: PC-38888Not For Human Use, Lab Use Only.
Adintrevimab (ADG20) is a fully human IgG1 monoclonal antibody targeting the highly conserved epitope on the receptor-binding domain (RBD) of S (spike) protein of SARS-CoV-2.
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Adintrevimab (ADG20) is a fully human IgG1 monoclonal antibody targeting the highly conserved epitope on the receptor-binding domain (RBD) of S (spike) protein of SARS-CoV-2.
Adintrevimab (ADG20) demonstrated an ability to potently neutralize SARS-CoV-2, including variants of concern, as well as a broad range of sarbecoviruses.
Adintrevimab (ADG20) exhibited broadly neutralizing the entire clade of SARS-like viruses from the sarbecovirus lineage, including diverse family members such as SARS-CoV-1, WIV1, SHC014 and SARS-CoV-2.
Isotype: IgG1-lambda2.
Anti-[human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein, receptor binding domain (RBD)], human monoclonal antibody.
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外观性状 | Solid | |
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10 mM in DMSO |
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1. Timothée Bruel, et al. Nat Med. 2022 Mar 23. doi: 10.1038/s41591-022-01792-5.
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