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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Carbonic Anhydrase-Acetazolamide
Acetazolamide

Chemical Structure : Acetazolamide

CAS No.: 59-66-5

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Acetazolamide (AAZ)

货号: PC-22967Not For Human Use, Lab Use Only.

Acetazolamide is a potent carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Acetazolamide is a potent carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX.
Acetazolamide inhibits the invasiveness of renal cell carcinoma in vitro by blocking hCA IX activity.
Acetazolamide shows diuretic, antihypertensive and anti-gonococcal activities.

物理化学性质&存储条件

分子量 222.24
分子式 C4H6N4O3S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Acetazolamide

参考文献

1. Hou Z, et al. Eur J Med Chem. 2017 May 26;132:1-10.

2. Gao H, et al. Oncol Lett. 2018 Jun;15(6):9299-9306.

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