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首页-小分子抑制剂&激动剂-Others-Other Targets-Acarbose
Acarbose

Chemical Structure : Acarbose

CAS No.: 56180-94-0

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Acarbose (BAY g 5421)

货号: PC-26815Not For Human Use, Lab Use Only.

Acarbose (BAY g 5421) is an antihyperglycemic agent and orally active alpha-glucosidase (α-glucosidase) inhibitor with IC50 of 11 nM, potentiates the hypoglycemic effects of sulfonylureas or insulin.

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500 mg ￥480 In stock
1 g ￥680 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Acarbose (BAY g 5421) is an antihyperglycemic agent and orally active alpha-glucosidase (α-glucosidase) inhibitor with IC50 of 11 nM, potentiates the hypoglycemic effects of sulfonylureas or insulin.

物理化学性质&存储条件

分子量 645.61
分子式 C25H43NO18
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal

参考文献

1. Yee HS, et al. Pharmacotherapy. 1996;16(5):792-805.

2. Zhang Q, et al. PLoS One. 2013 Nov 18;8(11):e79697.

3. Hanefeld M, et al. Expert Rev Cardiovasc Ther. 2008;6(2):153-163.

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