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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-mTOR-AcTor
AcTor

Chemical Structure : AcTor

CAS No.:

AcTor

货号: PC-26698Not For Human Use, Lab Use Only.

AcTor is a specific small molecule TSC2 inhibitor and mTOR stimulator, activates mTORC1 in the presence of ixazomib and potentiates ixazomibactivity across multiple AML cell lines.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    AcTor is a specific small molecule TSC2 inhibitor and mTOR stimulator, activates mTORC1 in the presence of ixazomib and potentiates ixazomibactivity across multiple AML cell lines.

    物理化学性质&存储条件

    分子量 907.16
    分子式 C48H58N8O6S2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    thiazol-5-ylmethyl ((2S,4R,5S)-6-(4-(1H-indol-3-yl)phenyl)-4-hydroxy-5-((S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-4-morpholinobutanamido)-1-phenylhexan-2-yl)carbamate

    参考文献

    1. Pattanayak SP, et al. Res Sq [Preprint]. 2026 Apr 23:rs.3.rs-9405584.

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