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Ac-YVAD-cmk

Chemical Structure : Ac-YVAD-cmk

CAS No.: 178603-78-6

Ac-YVAD-cmk (Ac-YVAD-chloromethylketone, Caspase-1 inhibitor)

货号: PC-22752Not For Human Use, Lab Use Only.

Ac-YVAD-cmk is a tetrapeptide, selective caspase-1 (interleukin-1 beta converting enzyme, ICE) inhibitor with neuroprotective and anti-inflammatory effects, inhibits pyroptosis (caspase-1-activated cell death).

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10 mg ¥3880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ac-YVAD-cmk is a tetrapeptide, selective caspase-1 (interleukin-1 beta converting enzyme, ICE) inhibitor with neuroprotective and anti-inflammatory effects, inhibits pyroptosis (caspase-1-activated cell death).

物理化学性质&存储条件

分子量 541.00
分子式 C24H33ClN4O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-Acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-L-alaninamide

参考文献

1. Dubrez L, et al. EMBO J. 1996 Oct 15;15(20):5504-12.

2. Yang M, et al. Biomed Res Int. 2021 Jun 10;2021:6636621.

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