Ac-IEPD-CHO | Granzyme B inhibitor | Probechem Biochemicals

Chemical Structure : Ac-IEPD-CHO

CAS No.: 352520-90-2

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Ac-IEPD-CHO (Ac-Ile-Glu-Pro-Asp-CHO)

货号: PC-35176Not For Human Use, Lab Use Only.

Ac-IEPD-CHO (Ac-Ile-Glu-Pro-Asp-CHO) is a potent, reversible inhibitor of serine protease Granzyme B (GzmB) with Ki of 80 nM, also inhibits caspase-7 (Ki=550 nM) and induces apoptosis.

规格	价格	库存
5 mg	￥3580	In stock
10 mg	￥5580	In stock
25 mg	￥8980	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Ac-IEPD-CHO (Ac-Ile-Glu-Pro-Asp-CHO) is a potent, reversible inhibitor of serine protease Granzyme B (GzmB) with Ki of 80 nM, also inhibits caspase-7 (Ki=550 nM) and induces apoptosis.

物理化学性质&存储条件

分子量	498.533
分子式	C22H34N4O9
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-Acetyl-L-isoleucyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-L-prolinamide

参考文献

1. Shen Y, et al. Exp Mol Med. 2018 May 30;50(5):68.
2. Velthuis JH, et al. Immunobiology. 2003;207(2):115-27.

Ac-IEPD-CHO (Ac-Ile-Glu-Pro-Asp-CHO)

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Ac-IEPD-CHO (Ac-Ile-Glu-Pro-Asp-CHO)

生物&药学活性

物理化学性质&存储条件

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