Chemical Structure : Abciximab
CAS No.: 143653-53-6
货号: PC-Ab1095Not For Human Use, Lab Use Only.
Abciximab (Abcixifiban.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Abciximab (Abcixifiban; c7E3 Fab) is a monoclonal anti-glycoprotein IIb/IIIa receptor antibody antagonist, prevents platelet aggregation by blocking glycoprotein IIb/IIIa receptors on their platelet's plasma membrane and inhibits fibrinogen binding. It exerts it`s action by steric hindrance of the receptor itself and prevents platelet aggregation and subsequent thrombus formation and blocking interaction of fibrinogen. It also inhibits vitronectin receptor which mediates both platelet coagulation as well as endothelial and vascular smooth muscle proliferation.
分子量 | ||
分子式 | Human IgG1 Fab-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Abciximab; Reopro; Abcixifiban;143653-53-6; c7E3 Fab; Anti-human Glycoprotein IIb/IIIa; Anti-human GP IIb/IIIa; Anti-human glycoprotein receptor |
1. 1, Faulds D, et al. Drugs. 1994 Oct;48(4):583-98. 2, Kereiakes DJ, et al. Am J Cardiol. 1996 Nov 15;78(10):1161-3. 3, Kereiakes DJ, et al. Circulation. 1996 Sep 1;94(5):906-10. 4, Le Breton H, et al. J Am Coll Cardiol. 1996 Dec;28(7):1643-51.
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