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首页-抗体和重组蛋白-Other Fusion Proteins-Abatacept
Abatacept

Chemical Structure : Abatacept

CAS No.: 332348-12-6

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Abatacept (CTLA4lg, BMS-188667)

货号: PC-28462Not For Human Use, Lab Use Only.

Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extracellular domain of human CTLA4 linked to the Fc portion of IgG1 (hinge and CH2 and 3 domains), is a selective costimulation modulator that inhibits T cell activation by competing with CD28 for CD80 and CD86 binding.

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2 mg ￥5280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extracellular domain of human CTLA4 linked to the Fc portion of IgG1 (hinge and CH2 and 3 domains), is a selective costimulation modulator that inhibits T cell activation by competing with CD28 for CD80 and CD86 binding.

物理化学性质&存储条件

分子量 84.4 kDa
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Linsley PS, et al. Science. 1992 Aug 7;257(5071):792-5.

2. Lenschow DJ, et al. Science. 1992 Aug 7;257(5071):789-92.

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