AZD7009 |CAS:864368-79-6 Probechem Biochemicals

Chemical Structure : AZD7009

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AZD7009 (AZD-7009)

货号: PC-63155Not For Human Use, Lab Use Only.

AZD7009 is an antiarrhythmic agent that inhibits the late sodium current in CHO K1 cells expressing hNav1.5 with IC50 of 11 uM.

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生物&药学活性

AZD7009 is an antiarrhythmic agent that inhibits the late sodium current in CHO K1 cells expressing hNav1.5 with IC50 of 11 uM.
AZD7009 also inhibits late sodium current in isolated rabbit atrial and ventricular myocytes, attenuates the E-4031-induced action potential duration prolongation, induces early afterdepolarisations (EADs) in Purkinje fibres.

物理化学性质&存储条件

分子量	446.548
分子式	C23H34N4O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	tert-butyl N-[2-[3-[(2S)-3-(4-cyanophenoxy)-2-hydroxypropyl]-9-oxa-3,7-diazabicyclo[3.3.1]nonan-7-yl]ethyl]carbamate

参考文献

1. Goldstein RN, et al. J Cardiovasc Electrophysiol. 2004 Dec;15(12):1444-50.

2. Persson F, et al. J Cardiovasc Electrophysiol. 2005 Mar;16(3):329-41.

3. Persson F, et al. J Cardiovasc Pharmacol. 2005 Jul;46(1):7-17.

4. Persson F, et al. Eur J Pharmacol. 2007 Mar 8;558(1-3):133-43.

AZD7009 (AZD-7009)

生物&药学活性

物理化学性质&存储条件

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AZD7009 (AZD-7009)

生物&药学活性

物理化学性质&存储条件

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