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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Matrix Metalloproteinase (MMP)-AZD6605
AZD6605

Chemical Structure : AZD6605

CAS No.: 893556-15-5

AZD6605 (AZD-6605)

货号: PC-28296Not For Human Use, Lab Use Only.

AZD6605 (AZD-6605) is a potent and selective inhibitor of MMP-13 (MMP13) with IC50 of 4.7 nM, 430-fold selective over MMP-14.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

AZD6605 (AZD-6605) is a potent and selective inhibitor of MMP-13 (MMP13) with IC50 of 4.7 nM, 430-fold selective over MMP-14.

物理化学性质&存储条件

分子量 483.44
分子式 C18H21F4N3O6S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,4-Imidazolidinedione, 5-methyl-5-[[[4-[4-(1,1,2,2-tetrafluoroethoxy)phenoxy]-1-piperidinyl]sulfonyl]methyl]-, (5S)-

参考文献

1. De Savi C, et al. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4705-12.

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